ABSTRACT
An antifungal compound 9, 10-dihydrophenanthrene - 2 - carboxylic acid was isolated from a marine derived bacterium Pseudomonas putida isolated from surface water samples of Karachi fish harbor coast line. The structure was explored using extensive 1D- and 2D-NMR spectroscopic techniques. The compound was found to be active against fungal strains obtained from clinical samples whereas strong activity was noted against Candida albicans with a MIC value of 20microg/ml, as the purified compound showed promising anticandidal activity a multidisciplinary approach is needed to explore further this compound as potential pharmacological lead compound against Candida spp and will add in the global hunt for clinically functional antifungal agents
ABSTRACT
To observe the effect of low vision devices [LVDs] i.e. 2.5x vista view, 4x telescope and magnifying glasses on distance visual acuity of children with low vision. This observational study was conducted in the department of Pediatric Ophthalmology and Low Vision Clinic at Al-Shifa Trust Eye Hospital. 40 children with impaired visual acuity from ages 5 to 18 years were included in the study. All children had detailed anterior and posterior segment examination by pediatric ophthalmologists while LVDs were prescribed in low vision clinic. All children fulfilling WHO criteria for low vision were provided with 2.5 X vista view, 4x telescopes and magnifying glasses for improving far vision. ANOVA was used to find out which low vision device is more effective in visual improvement either glasses or telescopes i.e. vista view and 4X. Out of 40 children 20[50%] children were males and 20 [50%] were females. Main cause of low vision in our study came out to be albinism. Our study states that 4x telescope is the most effective device to improve distant visual acuity in children with low vision. Low vision aids are essential and effective for the children with low vision. They not only improve the visual acuity but also help in the education through visual rehabilitation